Toronto Organ Preservation Laboratory

Christian Hobeika

Dr. Christian Hobeika (M.D., Ph.D.) graduated from Medical School in 2013 at the University of Strasbourg, France. He is a trained surgeon who completed his residency at the Academic Hospitals of Paris (APHP) in France between 2013 and 2019 for which he was awarded the Medal of surgical residency (APHP, Sorbonne University, Paris). He achieved two clinical fellowships in HPB surgery and liver transplantation at Beaujon Hospital (Paris-Cité University, APHP, Clichy, France) and at La Pitié-Salpêtrière Hospital (Sorbonne University, APHP, Paris, France) under the mentorships of Prof. Olivier Soubrane and Prof. Jean-Christophe Vaillant, between 2019 and 2022. He completed a master’s degree at Paris-Est University (Creteil, France) investigating the anti-tumoral effect of an anti-TGFß targeted therapy in hepatocellular carcinoma in 2015. In 2022, he defended his Ph.D. at Paris-Cité University (Paris, France) studying the liver transcriptome of a hepatocellular carcinoma mouse model induced by SV40 T antigen expression. Dr. Hobeika's publications and research interests encompass the areas of HPB oncologic surgery, liver transplantation, minimally invasive approaches, oncogenomics, immunotherapies, and computational biostatistics.

In 2023, he joined the Toronto Organ Preservation Laboratory as a fellow, pursuing post-doctoral research. Dr. Hobeika investigates the therapeutic and immunomodulatory effects of graft-targeted regulatory T-cell therapy using a porcine model of liver transplantation with ex-vivo normothermic liver machine perfusion.

Publications and research work: